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KMID : 1030220140150020082
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Journal of Korean Diabetes
2014 Volume.15 No. 2 p.82 ~ p.92
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Diagnosis of Non-alcoholic Fatty Liver Disease
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Gwak Geum-Youn
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Abstract
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Although the classical gold standard for diagnosing and staging non-alcoholic fatty liver disease (NAFLD) and assessing fibrosis is liver biopsy, the procedure has several drawbacks, such as sample error, subjectivity in interpretation, high cost, and a small but real risk of complications.In an attempt to replace liver biopsy and to subcategorize patients with NAFLD into different prognoses, many non-invasive methods using various biomarkers, scoring systems, and imaging methods, such as elastography, have been attempted in the last decade. This article summarizes non-invasive diagnostic tests for the diagnosis of NAFLD/Nonalcoholic steatohepatitis, as well as the limitations and merits of liver biopsy.
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KEYWORD
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Non-alcoholic fatty liver disease, Nonalcoholic steatohepatitis, Diagnosis, Liver biopsy
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